For millennia, the evil Galra empire has plagued the universe by destroying other civilizations and enslaving various races. The only known threat strong enough against the empire's power and plans is the legendary "Defender of the Universe" Voltron, a 100 meter tall robot warrior composed of five lion mechas whose pilots are known as the Paladins. At the crux of the war that ended with the destruction of planet Altea, Voltron was separated by King Alfor of Altea in order to protect Voltron from falling into the Galran Emperor Zarkon's possession. King Alfor bonded the five lion's energies to his daughter Allura's life force and sent them across the universe to different locations until the time for the next generation of Paladins to appear and pilot Voltron arrived. Princess Allura, her retainer Coran, and the Altean Castle of Lions were hidden on planet Arus along with the Black Lion.
In the present, the Galra Empire's path of conquest and search for Voltron has led them to Earth's solar system. A group of space pilots – Shiro, Keith, Lance, Pidge, and Hunk – discover the Blue Lion and immediately get swept up into the Galran War. They meet Princess Allura, become the next Paladins, and reunite the five lions to form Voltron and combat Emperor Zarkon's nefarious schemes, with the hopes of ultimately defeating the entire Galra Empire.
- Defenders of the Universe
- Shiro: Leader of the Paladins of Voltron, Shiro is a natural, calm, decisive leader and always in control.
- Pidge: A technical genius, Pidge is the smartest member of the team
- Hunk: A gentle giant with an equally large appetite, Hunk is the heart of the team, lifting them up and making peace between them.
- Keith: Sullen and temperamental, Keith spends his free time honing his skills for battle.
- Lance: Cocky and confident, Lance is the class clown of the Defenders and likes to think of himself as a ladies' man.
- Allura: A Gentle but strong and determined princess and a friend to all, Allura wishes more than anything to finish her father's work in stopping Zarkon.
- Coran: Energetic and excitable despite his odd and quirky character, Coran is a reliable and steadfast ally to his princess and the Paladins.
- The Galra Empire
- Zarkon: A ruthless emperor of the Galra Empire, Zarkon is the lord and master of most of the known universe.
- Haggar: A mysterious and despicable witch as well as Zarkon's primary adviser, Haggar is both a dangerous sorceress and a mad scientist.
- Lotor: A mysterious Prince who is just like his father, Lotor places value in the strength of his allies.
- Galra Commander on Olkarion
- Beta Traz Warden
- Galra Sentries
- The Balmerans
- The Blade of Marmora
- Galaxy Garrison
- The Mer Aliens
- This is the fourth DreamWorks Classics television show and The first three being VeggieTales in the House, The Mr. Peabody & Sherman Show and Noddy, Toyland Detective.