Nana is a minor villain in the Madagascar 1, and the secondary antagonist of Madagascar: Escape 2 Africa. She is an old woman, who always beats Alex with her handbag (which she loves).
Nana seems to be incredibly resistant to injury as she was able to have a short fight with Alex right after being tugged out of the back of a speeding tour jeep (as well as being thrown out of it a 2nd time by the Penguins, who reversed over her in the jeep after noticing that she didn't die). However, despite this evident resilience, Nana is still portrayed as a "little old lady".
Nana has a waddling gait and is knocked onto her back when firing a rifle.
You're a bad kitty
In Madagascar Nana plays very little part in this entry. She encounters Alex in the Grand Central Station, where she assaults him and calls him "a bad kitty (including Melman) she is seen when the policeman arrived he assaults Alex again and was arrested
She is also seen during the end credits dancing the song I'd like to Move it
The Madagascar Penguins in a Christmas Caper
Now, now, Mr. Chew, you have to wait until morning to open your chistmas presents
-Nana After wrapping up Private
She also appears in the Madagascar Penguins in a Christmas Caper as the women who buys Private.
Madagascar Escape 2 Africa
-Nana carrying her riffle
In Madagascar: Escape 2 Africa Nana has a larger role, where she is the secondary antagonist. She becomes the leader of an army of tourists. She gets into another fight with Alex, and wins again, although Alex puts up much more of a fight this time. At the end of the film, Alex gives Makunga Nana's handbag. When Nana sees Makunga holding it, she starts kicking, stepping, hand-whacking, wet-willying, arm-burning, and spanking him before taking him away.